Low Dose Naltrexone for the
Treatment
of Fibromyalgia
About the Study
Fibromyalgia is a common and potentially debilitating condition that can negatively impact every area of a person’s life. Little in known about the disorder, and there is still a great need for effective treatments.
We are investigating whether low-dose naltrexone (LDN) is one such treatment that many alleviate the symptoms of fibromyalgia (pain, fatigue, weakness, sleep disorders, problems concentrating). LDN may work be restoring balances in the nervous and immune systems.
While some physicians have been using LDN for many years to treat Fibromyalgia and other disorders, there has never been a scientific study of how well the drug works in fibromyalgia. Studies such as this are a necessary step to having an investigational drug become a mainstream treatment. Your participation is a vital part of the search for an effective fibromyalgia treatment.
This study is being funded by the non-profit organization: the American Fibromyalgia Syndrome Association (AFSA). There are no pharmaceutical industry or business interests involved in this study.
About Your Participation
- The entire project takes 22 weeks to complete.
- You will take low-dose naltrexone (LDN) or placebo once daily for a total of 16 weeks.
- Short checkup visits at Stanford will be scheduled for every 2 weeks.
- Study medications and clinical evaluations will be provided at no cost to you.
- A short (< 2 minute) questionnaire will be completed daily on a handheld computer.
- Your participation is totally voluntary and you can withdraw from the study at any time.
About The Stanford Systems Neuroscience and Pain Lab (SNAPL)
The SNAPL team at Stanford, together with Stanford Hospital’s Pain Management Center, is a collection of experienced physicians and researchers from a number of pain-related fields: psychology, anesthesiology, neurology, physical rehabilitation, psychopharmacology, and neuroscience. In our active research program, we test the most advanced treatment options for pain. We are heavily involved in unlocking the mysteries of pain so as to develop the best possible care for patients today and in the future.
Benefits to Participants
- Be part of research that may guide the development of future fibromyalgia and pain medications
- Interact extensively with the research team, which includes leaders in the field of pain management
- Potential pain relief for fibromyalgia sufferers from the study medication
Eligibility
- Men and women
- Age 18-65
- Must currently have daily pain throughout the body
-
Must live close to the Bay Area and be able to attend lab sessions every other week
Compensation
Participants will earn $600 for their time and travel expenses.
Location
780 Welch Road, Room 208C
Palo Alto, CA 94304
Consent Form
The consent form is a document that explains all aspects of the study to potential participants. The consent form can be downloaded and reviewed (PDF).
Contact
Stanford Systems Neuroscience and Pain Lab (SNAPL)
Phone: (650) 724-0522
Participation Survey
If you are interested in participating, please complete the secure screening survey by clicking on the link below.
COMPLETE THE SCREENING QUESTIONNAIRE
Questions about Research
For further information regarding questions, concerns, or complaints about research, research related injury, and questions about the rights of research participants, please call (650) 723-5244 or call toll free 1-866-860-2906, or write the Administrative Panel on Human Subjects in Medical Research, Administrative Panels Office, Stanford University, Stanford, CA 94305-5401.
